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CAS Number: 936563-96-1

Formula: C25H24N6O2 

Molecular Weight:  440.507

Method of Analysis:In house


Chronic Lymphocytic Leukemia (CLL), Mantle Cell Lymphoma (MCL) 


Ibrutinib is a small-molecule inhibitor of BTK. Ibrutinib forms a covalent bond with a cysteine residue in the BTK active site, leading to inhibition of BTK enzymatic activity. BTK is a signaling molecule of the B-cell antigen receptor (BCR) and cytokine receptor pathways. BTK's role in signaling through the B-cell surface receptors results in activation of pathways necessary for B-cell trafficking, chemotaxis, and adhesion. Nonclinical studies show that ibrutinib inhibits malignant B-cell proliferation and survival in vivo as

well as cell migration and substrate adhesion in vitro.

Storage conditions:

stor in light-resistant and well closed container .protect from air and moisture ,at a temperature of 2-8ᵒC


The final product is packed in polyethylene nylon plastic bag and then packaged in a 3-layered aluminum foil.